cagrilintide vs semaglutide VisualAbstract: Cagrilintide-Semaglutide is Effective for Weight Loss in Adults with Overweight or Obesity and Type 2 Diabetes Cagrilintide is a long-acting amylin

Given the relatively smaller reduction in body weight (9.4%) in the SELECT trial compared to previous RCTs: 14.9% in STEP1 (BMI 37.86.7 kg/m 2 ) [16] and 13.2% STEP6 (BMI 31.9 kg/m 2 ) [49], pleiotropic effects of semaglutide may contribute to the overall CV risk reduction [25,37]

Late responders had lost less than 5 percent but, crucially, 90 percent of them went on to achieve 5 percent or greater weight loss by week 72

Providers who compete on low headline numbers often make up the difference through dose-based pricing, mandatory commitments, separate fees, and opaque pharmacy sourcing

Drinking sugary beverages has also been linked to increased triglyceride levels, which is unsafe for those with diabetes and can cause negative side effects if taken alongside semaglutide medication

Accessed June 17, 2025.