Endocrinology 107:15301535 Talbott SM, Cifuentes M, Dunn MG, Shapses SA (2001) Energy restriction reduces bone density and biomechanical properties in aged female rats
"When I talk to patients about weight management, I always bring up these other options as well, because some people don't want to use a needle." Older prescription weight loss pills include: Hydrogel ( Plenity ) Naltrexone-bupropion ( Contrave ) Orlistat ( Xenical ) Phentermine (Adipex, Suprenza) Phentermine topiramate (Qsmyia) While the GLP-1 agonists can produce a weight loss of 10% to 20%, the average weight lost with older medications is lower in the range of 5% to 10% of the starting body weight
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There are two principal incretin agents: GIP and GLP-1
Avoid products with "proprietary blends" that hide their exact ingredient lists