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The previous study showed that fibroblasts isolated from individuals with HGPS demonstrate lamin A has an ability to repair DNA lesions (Burtner and Kennedy, Mutation in lamin A/C ( LMNA ) has been identified as the target gene for HGPS

Cell and Tissue Research (2019) 4

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Isopropyl myristate (IPM) has been widely used in topical pharmaceutical formulations for enhancing drug solubility and biomembrane penetration [44]

The delivery system preferably is a gel-based system