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Doses are adjusted slowly and thoughtfully, only in small increments and only when theres a clear reason to do so, says Class

Talk with your clinician before experimenting if you have: GERD that's active or difficult to control Gallbladder disease or a history of gallstones (rapid weight loss itself can raise gallstone risk, and fatty meals can provoke symptoms) A history of pancreatitis or significant pancreatic disease IBS that's currently flaring, especially if you're reacting to multiple foods or supplements While there's no well-established drug interaction between semaglutide and typical digestive enzyme products, your overall clinical context matters

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