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GSHhematin adducts were proposed to be formed via the withdrawal of the respective stabilizing ions yielding the same molecular ion [72] (thus bearing identical fragmentation spectra)

This suggests that CD63-mediated packaging at endosomes may result in protein degradation or misfolding, given that endosomes serve as sites for protein degradation

The lysine residue's positive charge facilitates interaction with glycosaminoglycans and negatively charged phospholipids in cellular membranes, enhancing uptake efficiency