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Abbreviations 8-OHdG: 8-hydroxy-2-deoxyguanosine CNS: central nervous system DI: damage index DCF: dichlorofluorescein DMEM: Dulbeccos modified Eagle medium G6PD: glucose-6-phosphate dehydrogenase H 2 DCF-DA: 2,7- dichlorofluoresceindiacetate H 2 O 2 : hydrogen peroxide L-car: L-carnitine LNAA: large neutral amino acids OCTN2: carnitine/organic cation transporter PAA: phenylacetic acid

Finally, we screened reference lists from relevant published studies

It provides neuroprotection against reactive oxygen species generated, for example, from high oxidative metabolism in neurons 36

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