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In Nederland is medicatie uitsluitend op recept verkrijgbaar, en een geldige artsenverklaring is wettelijk verplicht
Its highly effective but extremely hazardous, with strictly regulated handling and disposal requirements
Diabetes 58, 15091517
In vitro experiments demonstrated that agrin treatment significantly downregulated PDGFR and claudin-5 expression in a blood-brain barrier co-culture model comprising human brain microvascular endothelial cells and pericytes, suggesting that agrin may induce pericyte death and impair the integrity of the blood-brain barrier
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