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Patients should maintain adequate hydration, particularly if experiencing vomiting or diarrhoea

Antioxidant activity is mainly responsible for depigmenting action of glutathione, and it reduces the formation of reactive oxygen species in the skin cell after exposure to UV rays and environmental pollutants, thus reducing the risk of melanogenesis

Materials and methods Study population and patient preparation The study included 804 patients who visited the outpatient department of endocrinology at Kawasaki Medical School Hospital between January 1, 2010, and December 31, 2021, for abnormal thyroid-stimulating hormone (TSH) or free triiodothyronine (FT3) or free thyroxine (FT4), or for thyroid gland enlargement

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Another may have hard stool, straining, bloating, and abdominal pressure