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GLP1RAs have a significant role in the therapeutic regimen of T2D with Obesity &/or Metabolic syndrome

323 Notably, metastasis-initiating CSCs often undergo EMT, acquiring a more plastic and adaptable phenotype that enables their survival in circulation and adaptation to new microenvironments

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BRIN-BD11 cells were used throughout this study for their well characterised responses to multiple stimuli, cell culture based convenience and their established intact response to GLP-1R activation both in terms of cAMP and resulting stimulated insulin secretion 36, 37

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