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Pharmacological Reviews October 2016, 68 (4) 954-1013

This was evident by the inhibition of JNK, ERK and p38 phosphorylation and downregulation of cyt- C, Bax, cleaved CASP-3 and upregulation of BCL2 [139]

Key interventions include: Airway Management : Ensuring a clear airway is important, especially in patients with impaired consciousness, to prevent aspiration and maintain adequate ventilation

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