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E may also directly generate ROS by activating the NADPH oxidase (NOX) family, particularly NOX4 [57,58]

Liraglutide and dulaglutide seem to provide similar glycemic control, as do oral semaglutide and liraglutide

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The guideline reflects an acknowledgement that obesity is a chronic medical condition, not simply a behavioral issue, and that medication may be appropriate for some people as part of long-term care. But while the guidelines reflect positive changes in the perception of obesity, the WHOs own assessment of current evidence suggests the jury is still out on the long-term impact of GLP-1 use