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We don't have any data on these drugs and people with eating disorders, says Susan McElroy, a psychiatrist at the University of Cincinnati College of Medicine in Ohio, largely because obesity and eating disorders are still viewed in medicine as separate, rather than overlapping, conditions

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The SURMOUNT-1 study showed that participants lost an average of 15 to 20 percent of their body weight over 72 weeks

Clinical guidance notes that these foods can delay stomach emptying and relax the lower esophageal sphincter, making reflux more likely.69 For many, starting with these diet and lifestyle shifts and layering in prebiotics or probiotics as needed may make more sense than relying indefinitely on digestive enzyme supplements, especially in the absence of a clearly documented enzyme deficiency