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Carriers must use intensive behavioral therapy (IBT) prior to and while covering an AOM
The top 10 significantly enriched pathways include Glycerophospholipid metabolism, Choline metabolism in cancer, Insulin signaling pathway in cancer, Glycolysis/Gluconeogenesis, Central carbon metabolism in cancer, Alanine, aspartate and glutamate metabolism, Niacin and Niacinamide metabolism, -Alanine metabolism, Insulin resistance, and the AMPK (AMP-activated protein kinase) signaling pathway (Figure 5B)
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Current markers (e.g., GPX4, lipid peroxides, and serum iron) lack specificity for DN, as they are also altered in other kidney diseases or metabolic disorders
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