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Gastric Pentadecapeptide BPC 157 Accelerates Healing of Transected Rat Achilles Tendon and In Vitro Stimulates Tendocytes Growth Journal of Orthopaedic Research BPC 157 improved tendon healing biomechanically (increased load-to-failure and elasticity), functionally, and microscopically achieving superior fibroblast formation and collagen deposition

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It increases MMPs (e.g., MMP-2, MMP-9) activity and inhibits TIMPs (e.g., TIMP-1, TIMP-2) expression [149], promoting ECM degradation and reducing its accumulation