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Regular injections may promote even skin tone, improve energy levels, and enhance immune function

- [Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)]( *New England Journal of Medicine*, 2021

Mesotherapy is also effective against melasma

Because of this central role, SAMe ultimately plays a role in numerous methylation reactions catalyzed by methyltransferase enzymes including the synthesis of hormones, neurotransmitters, nucleic acids, proteins, and phospholipids (Mischoulon)

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