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doi: 10.3748/wjg.v31.i10.100194 42 GuoRLiYSongQHuangRGeXNietoNet al

Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Stop use if hypersensitivity occurs

Other Information: Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, peanut, or tree nut derived ingredients., Manufactured in a cGMP facility., 3rd PARTY TESTED

Taken together, the available literature supports the view of PD as a multisystem disorder involving complex bidirectional communication between the gut, immune system, and CNS, and highlights the gutimmunebrain axis as a potential therapeutic target [18]