Even after taking semaglutide for two years, some people still report feeling hungry or having food cravings, even though they have lost weight and have better control over their eating. A study of four semaglutide trials found that 33% of people lost 20% or more of their body weight, but many others experienced different levels of weight loss
Make sure to check with your provider, pharmacy, and insurer, and ask about patient assistance programs if cost is a concern
Environmental Factors: Weather conditions like extreme cold, heat, or wind can trigger skin sensitivity
When traveling, the medication should be transported in an insulated container with ice packs if refrigeration will not be available, taking care to prevent direct contact between the medication and ice to avoid freezing
In a recent phase 3 trial with patients with T2D and inadequate glycaemic control, the mean percentage change from baseline body weight with the 12-mg dose of retatrutide at 40 weeks was -15.3% [19]