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Results: We observed a significant increase in the levels of glutamine, taurine, glutathione, and xanthine, and a significant decrease in the branched-chain amino acids, valine, and isoleucine, as well as glutamate and cysteine in the tamoxifen-resistant cells compared to tamoxifen sensitive cells

Hydrogen/Deuterium exchange-protected oligomers populated during A fibril formation correlate with neuronal cell death

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This highlights the importance of cautious dosage determination and rigorous monitoring during administration to prevent any adverse outcomes that might arise from an overzealous eradication of senescent cells