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Results At 6 months follow-up the median absolute HbA 1c reduction was 5.3 mmol/mol (IQR 13.9, 1.0) (0.49% [1.27, 0.09]) and relative body weight reduction was 1.43% (4.26, 0)

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Evidence regarding naltrexone/bupropions cardiovascular effects remain inconclusive, following publication of the results for the prematurely terminated LIGHT outcomes study