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23 , 24 Additionally, mean baseline BMI in PIONEER (30.6 kg/m 2 ), SUSTAIN (30.8 kg/m 2 ), and STEP (35.3 kg/m 2 ) was higher than in evoke and evoke+ (25.7 kg/m 2 )

The potential drawback of nighttime injection relates to sleep quality if gastrointestinal upset develops during sleep

If you are thinking about stopping Mounjaro, read our guide on what happens when you stop taking Mounjaro to understand what to expect

Methods In accordance with the PRISMA guidelines, a comprehensive systematic review and meta-analysis of RCTs was conducted, encompassing studies published up to January 2025

This could theoretically lead to more degradation of the drug in the stomach and slightly reduced bioavailability