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At 72 weeks, participants receiving Tirzepatide 5mg, 10mg, or 15mg achieved mean weight reductions of 15.0%, 19.5%, and 20.9% respectively, compared to 3.1% with placebo

These effects, along with reduced food intake, may cause dehydration or nutritional deficiencies that could worsen brain fog in some individuals

While GLP-1 medications directly target this pathway, plant compounds and dietary fibers may only influence it indirectly and to a far smaller degree

In the pivotal Raun et al

Kariya C, Chu HW, Huang J, Leitner H, Martin RJ, Day BJ: Mycoplasma pneumoniae infection and environmental tobacco smoke inhibit lung glutathione adaptive responses and increase oxidative stress