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These changes are comparable in magnitude and duration to similar changes observed during withdrawal from other abused drugs such as cocaine, opiates, amphetamines, and alcohol

Further study such as a murine smoke exposure model is necessary to demonstrate the effect of CSE on the intracellular iron pathway in-vivo

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To reduce smoking among older smokers, public health efforts should target older smokers by tailoring their messages to the unique behavioral and physiological characteristics of older adults

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