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Third, misplaced harm reduction beliefs persist despite evidence of comparable nicotine dependence and cardiovascular risks between NTPs and conventional cigarettes 7

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Previous studies had demonstrated that the biosynthesis of PAs were mainly regulated at the transcription level by transcription factors belonging to the basic helix-loop-helix (bHLH), R2R3-MYB, and WD-repeat protein families (Lepiniec et al., 2006

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