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[36] [37] Others include mouth soreness and dyspepsia (gum), nausea or heartburn (lozenges), as well as sleep disturbances, insomnia, and a local skin reaction (patches)

It impedes circulation and increases the chances of heart disease

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showed that CS-induced endothelial microparticles (EMPs) contained predominantly exosomes that were largely enriched in let-7d, miR-191, miR-126 and miR-125a [47], which may be important in predicting potential function of exosomes as paracrine effectors in patients with chronic obstructive pulmonary disease (COPD)

Some attempt to: Cover socket with gauze Avoid deep inhalation Rinse afterward However, these do not eliminate risk