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While there is a growing consensus that e-cigarettes are substantially less harmful than smoking and have the potential to generate substantial public health benefits at a population level if significant numbers of smokers switch from smoking to e-cigarette use [2, 3, 11, 12]

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Carisoprodol is classified as a Schedule IV controlled substance in the United States because one of its main metabolites, meprobamate, has sedative and addictive properties

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