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It is considered one of the leading causes of premature death according to Hatsukami, D

As late as the end of 1982, the company appears to have still hoped that it could preserve the Virginia plant: the 19821986 five-year program slated "$62.6 million to begin a modernization of the Petersburg plant and $50.6 million for a reconstituted tobacco plant" and observed that "by 1983 the latter will be economically attractive." However, even that plan offered a caution, declaring: "The currently envisioned improvements at Petersburg