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Moreover, careful reviews of lung cancer rates in mostly non-smoking populations (such as women in Asia), and in prospective studies has shown that rates of lung cancer among non-smokers are substantially lower than among smokers and have changed little over the last few decades (Thun et al., 2008)

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Conversely, for females we found the gap narrows with age, similar to observations in studies from the USA and Denmark [12, 13, 24]