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Britney Spears leaving tanning salon with cigarettes and lighter in hand Los Angeles, California - 03.11.07 Captions are provided by our contributors

The pleckstrin ( PLEK ) gene was the only upregulated gene shared by periodontitis and the comorbidities of UC, rheumatoid arthritis and cardiovascular diseases with fold-changes of 1.6, 1.8, 4.1 and 1.5, respectively74

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Additionally, antioxidants such as glutathione, which are crucial in protecting against oxidative stress, can be depleted by CS [274]