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If an open wound involves loss of skin and subcutaneous tissue, but has a base of healthy muscle, fascia, or tendon sheath, granulation tissue will form on the base and a split-thickness skin graft (STSG) can be applied, or the wound can be allowed to heal in from its sides (secondary intention)

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Transcriptome data showed that D103 treatment activated key drought-associated pathways, including glutathione metabolism and phenylpropanoid biosynthesis

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