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Our results suggest that e-cigarette use is associated with coronary vascular dysfunction at rest, even in the absence of physiologic stress, said Susan Cheng, MD, MPH, MMsc, director of Public Health Research at the Smidt Heart Institute and director of Cardiovascular Population Sciences at the Barbra Streisand Womens Heart Center

: are designed to accommodate longer cigarettes or multiple regular-sized cigarettes

doi: 10.1016/j.marpol.2016.10.023 97 StiegmanM.PictouS

This was copied by the population as a whole and by the early 1660s the habit was commonplace and starting to cause concern