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Once stuck in the pleura, these fibers cause: Chronic inflammation Genetic mutations (changes) Production of abnormal cellular proteins Free radical (oxidation) damage to the tissue A 2018 study published in Frontiers in Immunology details how asbestos fibers alter immune function
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Proteomics analysis also displayed increase in proteins and fatty acids biosynthesis, proteins post transcriptional modifications, chaperones and HSPs, proteins transportation across cell membrane and carbohydrates
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