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"For the patients who do survive, urgent treatment is required to seal off the aneurysm, as there is a very high risk of a second, often fatal bleed," Clarke wrote

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5.7 Angle-Closure Glaucoma The pupillary dilation that occurs following use of many antidepressant drugs including bupropion may trigger an angle-closure attack in a patient with anatomically narrow angles who does not have a patent iridectomy

While marketed as safer options, some may still contain harmful chemicals, and their health effects are not well studied