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However, there was a small decrease in smoking prevalence among 1624-year-olds, although this was not considered substantial after adjusting for other factors. A study from the UK found that the implementation of standardized packaging, including minimum pack sizes, did not significantly change the mean number of cigarettes consumed

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As between-study heterogeneity can be underestimated or even zero when the number of studies is small 196,197 , we used Fishers information matrix to estimate the uncertainty of the heterogeneity 198 and incorporated that uncertainty into the final results