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As far as we know it is the nicotine that causes the problems

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The development of regional or national cancer registries in low-income countries would provide a rich repository to study thyroid cancer in regions with varying environmental and social exposures

The causal chain of events linking smoking to genetic damage To answer the first question, let us consider the causal chain of events linking smoking to genetic damage: Emission of carcinogenic toxicants leads to exposure to carcinogenic toxicants, which in turn leads to metabolic responses to toxicant exposure, genotoxicity, and DNA damage

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