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40 Under severe stresses, mitochondria generate a large number of mtROS that cause an inflammatory response via several mechanisms, including tumor necrosis factor receptors (TNFRs), mitogen-activated protein kinase (MAPK), RIG-I-like receptors and NLR family pyrin domain-containing 3 (NLRP3) inflammasome signals

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Cigarette smoking, which is the most common form of tobacco use, is estimated to kill more than 8 million people worldwide (1)

The vaping debate remains complex, with the scientific community divided on the relative health risks