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The mean FTND score was significantly higher in the severe TUD group than in the non-TUD or moderate TUD groups ( p = 0.001)

Furthermore, their authorization has strict clauses about marketing and controlled distribution

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By integrating these mechanisms into a single conceptual framework, we aim to clarify the potential role of smoking-related exposures in shaping the synovial-cartilage microenvironment and to highlight key directions for future OA-specific mechanistic and translational research

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