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Common Causes Not enough tobacco in the chamber Uneven tobacco distribution Dry or crumbly tobacco Gaps or clumps in the chamber Tube not fully seated on the nozzle Incorrect pressure or packing method How to Fix It Spread tobacco evenly across the chamber

To induce Th17 cell differentiation, the cells were treated with TGF- (3 ng/mL), IL-6 (20 ng/mL), IL-23 (25 ng/mL), an anti-IL-4 antibody (5 g/mL), and an anti-IFN- antibody (Pepro Tech)