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"Smoking prevalence and attributable disease burden in 195 countries and territories, 19902015: a systematic analysis from the Global Burden of Disease Study 2015." The Lancet 389.10082 (2017): 1885-1906

The wax extraction process often uses Solvents like butane, isopropyl, or CO2 to pull the terpenes and cannabinoids from the weed plants

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However, key confounding variables such as lipid levels, diabetes, weight, body mass index and blood pressure were not included because their role in longevity was not understood at the time the study was designed and this is a limitation of the analysis