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However, first-time users could have to deal with spillage and leaking problems when refilling the tank for the very first time--- due to the smaller fill port

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The patent, which described the product as a nicotine-delivery device, noted that the tobacco in the product was optional

[] The reason for the association between the frequency of smoking and the degree of LOA could be that increased smoking frequency can aggravate nicotine dependence and that nicotine dependence can lead to increased smoking frequency