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In addition to funding tobacco prevention programs, these strategies include prohibiting all flavored tobacco products, significant tobacco tax increases, comprehensive smoke-free laws, hard-hitting mass media campaigns, and barrier-free insurance coverage for tobacco cessation programs

Evidence from the monocytic cell lines U937 and MM6 demonstrated that flavouring chemicals can evoke a number of direct harmful effects, including reduced cell viability and increasing pro-inflammatory cytokine production [58]

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Figure 1 summarizes the proposed mechanisms of e-cigarettes' effects on the cardiovascular system