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In the current study, galectin-8 dependent IL-6 induction in bronchial epithelial cells was shown to be significantly reduced by inhibiting PI3K, the predominant isoform in bronchial epithelial cells, rather than PI3K and PI3K

Particularly concerning is the fact that diacetyl is primarily found in flavored e-liquids which tend to be more appealing to teenagers

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Additionally, e-cigarettes stimulate epithelial cells to release -defensins, which are involved in inflammatory responses [50]