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Key benefits Whitening formula Removes stains caused by smoking, coffee or tea Deep cleaning Fresh mint flavor Gentle on enamel Specially formulated for smokers How to use Marvis Smokers Whitening Toothpaste Use a soft or medium bristle toothbrush Apply a small amount to a toothbrush and brush in circular motions for two minutes Rinse thoroughly Replace your toothbrush every 2-3 months

To reduce the effect of bias, we adjusted observations that did not account for more than five confounders, including age and sex, because they were the significant bias covariates identified by the bias covariate selection algorithm 29 (Supplementary Table 7)