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Digital and telephone support includes the NHS Quit Smoking app , which provides daily support, tracks progress, and offers motivational messages

Ventilation Holes : Tiny holes in the cigarette filter that allow air to mix with the smoke, diluting the concentration of nicotine and other chemicals

Cross-lagged longitudinal analysis The longitudinal association between phenotypes was explored using a classic two-wave cross-lagged panel model (implemented with the lavaan package version 0.8 in R) 64

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The results suggest that smoking is associated with brain volume loss, indicating a potential link between smoking and neurodegeneration