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113, 114 The involvement of extracellular ATP and uric acid and the activation of the Nalp3inflammasome complex in the abrogation of inhalational tolerance and induction of aberrant Th2-driven inflammation by cigarette smoke represents an interesting working hypothesis for further investigation
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A codified quality regime benchmark and sample approval, on-site workmanship inspections, and a controlled commissioning and handover that holds the standard to the final detail
