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Patient has a documented opioid dependence diagnosis (not merely opioid abuse or use) Current encounter does not involve active opioid withdrawal (use F11.23 if withdrawal is present) Patient is not documented as being in remission (use F11.21 if sustained remission is documented) No intoxication or intoxication delirium is present at this encounter Documentation reflects dependence-level physiological or behavioral criteria, not abuse-level criteria For practices managing opioid use disorder patients, compliance management tools that flag incomplete documentation before claim submission can significantly reduce F11.20-related denials

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