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Among very heavy drinkers, alcohol metabolism and the resulting inflammation may even contribute to serious brain damage, possibly including shrinkage of the brain or alcohol-induced dementia, Wakeman says

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She addressed the backlash during a subsequent episode of the show as Lea declared: Ill stop making jokes, Ill leave them to you. Clarifying that she was not making an apology for alcohol, Lea said the incident forced her to confront how a throwaway remark had opened a real societal debate while reflecting on the scale of the reaction to her joke