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Regarding the long-term effects of e-cigarette smoking on cardiac autonomic tone, a cross-sectional study comparing cases (e-cigarette users) and controls (healthy individuals with no history of smoking) who had used nicotine-containing e-cigarettes on most days for at least 1 year, showed a significant increase in sympathetic activity compared to the control group (30)

The distinction is critically dependent on carrier selection some carriers offer robust cigar exception language that allows applicants to qualify for non-smoker rates with disclosed cigar use, while other carriers apply tobacco classification to any cigar use regardless of frequency

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