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Interactions can also have a significant impact on the safety and efficacy profile of treatments, particularly if they compromise pharmacological activity and increase the odds of ADRs

To address this issue, the MG-CFA in the first step can be replaced with the multilevel confirmatory factor analysis (ML-CFA) using Bayesian estimation, which is more robust to small sample sizes (for details, see Zhao et al., 2025)

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Experiences and behaviours of patients with asthma requesting prescriptions from primary care during medication shortages linked to the COVID-19 lockdown: insights from a qualitative analysis of a UK asthma online community