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Every year, half a million Americans die from smoking-related causes, while an estimated 16 million Americans are living with smoking-related chronic health conditions, such as chronic obstructive pulmonary disease, heart disease, stroke, or cancer

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We have metalloproteinases which destroy our collagen cells, then we have tissue inhibitors of metalloproteinases (TIMPs), another enzyme which will counteract the effects of the MMPs. Impaired collagen production and skin repair Because smoking causes hyperexpression of the MMPs, it leads to an imbalance between the degradation and production of collagen cells in our skin, she states

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