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This effect was more pronounced as the proportion of men decreased

By using the web-based tool of MEXPRESS 63 , which has two main functions of Pearson correlation 64 and the non-parametric Wilcoxon rank-sum test 65 , we determined whether methylation probes were correlated with the extent of expression of the associated genes in both LUAD and LUSC samples and the different status of methylation loci correlated with RNA expression between control and cancer in LUAD or LUSC samples

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